John P Dowling Selected Research

IMM20184, IMM20190, and IMM20253 drug combination

1/2022

IMM-BCP-01, a patient-derived anti-SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA.1 and BA.2.

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John P Dowling Research Topics

Disease

3	Acute Kidney Injury (Acute Renal Failure) 10/2015 - 11/2006
2	COVID-19 01/2022 - 08/2021
2	Infections 01/2022 - 09/2004
2	Neoplasms (Cancer) 01/2016 - 01/2015
2	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 12/2012 - 10/2004
1	Birth Weight (Birth Weights) 01/2021
1	Albuminuria 01/2021
1	IGA Glomerulonephritis (IGA Nephropathy) 10/2015
1	Hemorrhage 10/2015
1	Hutchinson's Melanotic Freckle (Lentigo Maligna) 10/2011
1	Delayed Graft Function 09/2010
1	Hemolysis 11/2006
1	Fanconi Anemia (Fanconi's Anemia) 11/2006
1	Renal Insufficiency (Renal Failure) 10/2004
1	Hepatitis B 09/2004
1	Hepatitis 09/2004
1	Mixed Connective Tissue Disease (MCTD) 09/2004
1	Liver Failure 09/2004
1	HIV Infections (HIV Infection) 09/2004
1	Diabetic Nephropathies (Diabetic Nephropathy) 07/2003
1	Fibrosis (Cirrhosis) 07/2003
1	Wounds and Injuries (Trauma) 08/2002

Drug/Important Bio-Agent (IBA)

3	Proteins (Proteins, Gene)FDA Link 08/2021 - 07/2003
2	AntibodiesIBA 01/2022 - 08/2021
2	Antiviral Agents (Antivirals)IBA 01/2022 - 08/2021
2	Warfarin (Coumadin)FDA LinkGeneric 10/2015 - 08/2002
1	SARS-CoV-2 spike proteinIBA 01/2022
1	N-methyl-valyl-amiclenomycin (BA 2)IBA 01/2022
1	Broadly Neutralizing AntibodiesIBA 01/2022
1	Combined Antibody TherapeuticsIBA 01/2022
1	IMM20184, IMM20190, and IMM20253 drug combinationIBA 01/2022
1	Complement System Proteins (Complement)IBA 01/2022
1	N-(2-cyanoethylene)urea (BA 1)IBA 01/2022
1	AntigensIBA 08/2021
1	Viral ProteinsIBA 08/2021
1	Viral AntibodiesIBA 08/2021
1	neodymium pyrocatechin disulfonate (NPD)IBA 01/2021
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2016
1	Immunoglobulin A (IgA)IBA 12/2012
1	Imiquimod (Aldara)FDA LinkGeneric 10/2011
1	CC 401IBA 09/2010
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 11/2006
1	DNA (Deoxyribonucleic Acid)IBA 09/2004
1	Prednisolone (Predate)FDA LinkGeneric 09/2004
1	Chloroquine (Aralen)FDA LinkGeneric 09/2004
1	Protein Isoforms (Isoforms)IBA 07/2003
1	platelet-derived growth factor AIBA 07/2003
1	Peptides (Polypeptides)IBA 07/2003
1	Platelet-Derived Growth FactorIBA 07/2003
1	Messenger RNA (mRNA)IBA 07/2003
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2003
1	Etidronic Acid (HEDP)FDA LinkGeneric 08/2002
1	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 08/2002

Therapy/Procedure

2	Immunotherapy 01/2016 - 01/2015
2	Kidney Transplantation 09/2010 - 10/2004
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2015
1	Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation) 11/2006
1	Therapeutics 11/2006
1	Organ Transplantation 09/2004
1	Nephrectomy 07/2003
1	Hyperbaric Oxygenation 08/2002
1	Surgical Amputation (Amputations) 08/2002